Hyacinth Tablet


Marketed in India By

Magbro Healthcare

Koronis Pharmaceutical Pvt Ltd


Hyacinth tablets : iron 100 mg, folic acid 1.5 mg.


Vitamins & Minerals (Pre & Post Natal) / Antianemics

Folic Acid (Vit B9)

Therapeutic Class

Erythropoiesis agent


Treatment of megaloblastic anemia due to folic acid deficiency and in anemias of nutritional origin, pregnancy, infancy, or childhood.

Folate-deficient megaloblastic anaemia
Adult: 5 mg daily for 4 mth, up to 15 mg daily in malabsorption states. Continued dosing at 5 mg every 1-7 days may be needed in chronic haemolytic states, depending on the diet and rate of haemolysis.
Prophylaxis of megaloblastic anaemia in pregnancy
Adult: 0.2-0.5 mg daily.
Prophylaxis of neural tube defect in pregnancy
Adult: 4 or 5 mg daily starting before pregnancy and continued through the 1st trimester.
As supplement for women of child-bearing potential
Adult: 0.4 mg daily.


Undiagnosed megaloblastic anaemia; pernicious, aplastic or normocytic anaemias.

Warnings / Precautions

Treatment resistance may occur in patients with depressed haematopoiesis, alcoholism, deficiencies of other vitamins. Neonates.

Not for monotherapy in pernicious anemia and other megaloblastic anemias with B12 deficiency. May obscure pernicious anemia in dosage >0.1mg/day. Decreased B12 serum levels with prolonged therapy.

Adverse Reactions

GI disturbances, hypersensitivity reactions, bronchospasm, Allergic sensitization.

Drug Interactions

Antiepileptics, oral contraceptives, anti-TB drugs, alcohol, aminopterin, methotrexate, pyrimethamine, trimethoprim and sulphonamides may result to decrease in serum folate concentration. Decreases serum phenytoin concentrations.

Antagonizes phenytoin effects. Increased seizures with phenytoin, primidone, and phenobarbital reported. Tetracycline may cause false low serum and red cell folate due to suppression ofLactobacillus casei.

Mechanism of Actions

Acts as cofactor for transformylation reactions in biosynthesis of purines and thymidylates of nucleic acids; acts on megaloblastic bone marrow to produce normoblastic marrow; required for nucleoprotein synthesis and maintenance of normal erythropoiesis.
Onset: Peak effect: Oral: 0.5-1 hr.
Absorption: Rapidly absorbed mainly from the duodenum and jejunum.
Distribution: Extensively bound to plasma protein. Principal site of storage is the liver. It is also concentrated in the CSF and enters the breast milk.
Metabolism: Undergoes conversion in the plasma and liver to the metabolically active 5-methyltetrahydrofolate.
Excretion: Via urine (as unchanged drug and metabolites). Removed by haemodialysis.


Assess for alcoholism, chronic infection, and pernicious, megaloblastic, and hemolytic anemias, and for possible drug interactions.


Monitor for allergic/hypersensitivity reactions

Patient Counselling

Advise to seek medical attention if symptoms of allergic/hypersensitivity reaction occur.


Administration: Oral route.

Storage : 20-25°C (68-77°F).

Pregnancy Category

A: Drug Pregnancy Category Adequate and well-controlled human studies have failed to demonstrate a risk to the fetus in the first trimester of pregnancy (and there is no evidence of risk in later trimesters

ATC Classification


GenericPedia Classification

  • Vitamin B Complex ,
  • Vitamins & minerals



Packing (Max Retail Price)

Hyacinth tab

10's (80 INR)