Nasosmart-OX Nasal Spray




Oxymetazoline hydrochloride.

Marketing in India

Koronis Pharmaceutical Private Limited .


Listed in Dosage.


Adult: Nasal Nasal congestion As 0.05% soln: Spray 1-3 doses into each nostril twice daily. OphthConjunctival decongestant As 0.025% soln: Instill 1-2 drops 6 hrly when needed.
Click to view oxymetazoline Dosage by Indications


Glaucoma; hyperthyroidism, heart disease (including angina), hypertension, advanced arteriosclerotic conditions. Children <6 yr.

Special Precautions

Pregnancy, lactation. Difficulty in urination secondary to prostate enlargement; DM.

Adverse Drug Reactions

Nasal drops or spray: Local stinging or burning, sneezing, dryness of mouth and throat. Prolonged or frequent use may cause rebound congestion. Headache, insomnia, tachycardia, hypertension, nervousness, nausea, dizziness, palpitation, arrhythmia. Eye drops: Dryness of eye.

Drug Interactions

Potentially Fatal: Hypertensive crisis with MAOIs.

Pregnancy Category (US FDA)

Category C : Either studies in animals have revealed adverse effects on the foetus (teratogenic or embryocidal or other) and there are no controlled studies in women or studies in women and animals are not available. Drugs should be given only if the potential benefit justifies the potential risk to the foetus.

Mechanism of Action

For details of the mechanism of action, pharmacology and pharmacokinetics and toxicology ... click to view oxymetazoline

CIMS Class

Nasal Decongestants & Other Nasal Preparations / Ophthalmic Decongestants, Anesthetics, Anti-Inflammatories

ATC Classification

S01GA04 - oxymetazoline ; Belongs to the class of sympathomimetics used as ophthalmologic decongestants.
R01AA05 - oxymetazoline ; Belongs to the class of topical sympathomimetic agents used as nasal decongestants.
R01AB07 - oxymetazoline ; Belongs to the class of topical sympathomimetic combination preparations, excluding corticosteroids. Used as nasal decongestants.



Packing (Max Retail Price)

Nasosmart-OX nasal spray

10 mg ;50 mcg x 1 puff x 100md (115.00 INR)