Nasosmart-OX Nasal Spray



Marketing in India

Koronis Pharmaceutical Private Limited




Listed in Dosage.


Adult: Ophth Conjunctival decongestant As 0.05-0.1% soln: Instill as directed. Nasal Nasal congestion As 0.1% soln: Instill into each nostril 2-3 times/day. Max duration: 7 days.


Angle closure glaucoma; dry rhinitis; post trans-sphenoidal hypophysectomy, trans-nasal, trans-oral surgery where dura mater is exposed.

Special Precautions

Young children, pregnancy and lactation. Hypertension, CV abnormalities, DM, hyperthyroidism, history of excessive reaction to sympathomimetics, difficulty in urination secondary to prostate enlargement. Rebound congestion may occur after prolonged regular use.

Adverse Drug Reactions

Headache, insomnia, tachycardia, hypertension, nervousness, nausea, dizziness, palpitation, arrhythmia. Nasal drops: Local stinging or burning, sneezing, dryness of mouth and throat, nausea. Eye drops: Dryness of eye.

Drug Interactions

Increased heart rate or BP with sibutramine.
Potentially Fatal: Hypertensive crisis with MAOIs.

Mechanism of Action

Xylometazoline is a direct-acting sympathomimetic which has a vasoconstrictor effect by reducing swelling and congestion when applied to mucous membranes.
Onset: 5-10 min.
Duration: 10 hr.

CIMS Class

Nasal Decongestants & Other Nasal Preparations / Ophthalmic Decongestants, Anesthetics, Anti-Inflammatories

ATC Classification

S01GA03 - xylometazoline ; Belongs to the class of sympathomimetics used as ophthalmologic decongestants.
R01AA07 - xylometazoline ; Belongs to the class of topical sympathomimetic agents used as nasal decongestants.
R01AB06 - xylometazoline ; Belongs to the class of topical sympathomimetic combination preparations, excluding corticosteroids. Used as nasal decongestants.



Packing (Max Retail Price)

Nasosmart-XL nasal drops

0.1 % w/v x 10ml (56.00 INR)